GenomeRNAi - a database for RNAi phenotypes and reagents

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News

1 June
2016

GenomeRNAi v16 released

GenomeRNAi 16.0 takes the total of human RNAi screens to 467, and to 207 in Drosophila. The number of gene-phenotype associations has increased to over 2,7 million. Many thanks to Hosono et al. who submitted a screen on Drosophila airway maturation. Try out our new interactive graphical representation of gene-phenotype relationships (example)!
11 January
2016

GenomeRNAi v15 released

Thanks to the import of the Broad Institute's Achilles Project , the number of gene-phenotype associations has more than doubled to over 2,5 million entries. The database now provides data from 452 human RNAi screens and 201 screens in D.melanogaster.
NEW: Try out our full page view with a download option to obtain all phenotypes for a given gene or reagent!
30 April
2015

GenomeRNAi version 14 released

GenomeRNAi 14.0 is a data release. The database now contains 217 RNAi screens in human, and 201 screens in Drosophila. The total number of gene-phenotype associations has increased to over 1,2 million. Many thanks to V. Gama who submitted a screen on Cytochrome c degradation and to A. Cole who submitted a Lentiviral shRNA 'Achilles Heel' screen.
24 June
2014

GenomeRNAi version 13 released

This is a data release. The database now features 194 RNAi screens in human, and 183 screens in Drosophila. The total number of gene-phenotype associations has increased to over 950,000. We have also implemented links to EuropePMC. Many thanks to Gilad Sivan who submitted a genome-wide screen on vaccinia infection. As ever, we welcome your own data submission!
29 January
2014

GenomeRNAi version 12 released

This release features 168 RNAi screens in human, and 181 screens in drosophila, as well as a NEW functionality - overlay genes sharing the same phenotype onto networks in StringDB. GenomeRNAi is recommended data repository by Nature’s new “Scientific Data“ publication format. Looking forward to your RNAi data submissions! Europe PMC provides links to GenomeRNAi - check out the current list.
8 August
2013

GenomeRNAi version 11.1 released

This release gives access to a beta version of our NEW screen comparison tool. We'd really appreciate your feedback very early on in the development of this new feature. TEST IT OUT and LET US KNOW what we should add or change and how you'd ideally like to use this functionality!
We'd also appreciate if you could take just a few minutes to complete our user survey!
12 June
2013

GenomeRNAi version 11 released

This release features a new data submission functionality: data submitters are provided with their own login space for uploading and viewing their data, and for sharing them with colleagues/reviewers. Frequent hitters can now be filtered by number or percentage of hits. The database contains 145 RNAi screens in human, and 174 screens in drosophila.
24 January
2013

GenomeRNAi version 10 released

GenomeRNAi 10.0 is a data release providing newly curated phenotype data: The database now contains 137 RNAi screens in human, and 173 screens in drosophila. We thank Rebecca Saunders for submitting a genome-wide screen on Hippo pathway regulation!
3 December
2012

GenomeRNAi paper in NAR database issue

A description of the GenomeRNAi database and website is now online in the latest NAR database issue.
25 October
2012

GenomeRNAi version 9.1 - minor update

This is a minor update affecting mainly the Frequent hitters page. We have introduced a new column indicating the reagents that have been reported to produce the phenotypes. In addition, the frequent hitter list is now available for download.
21 September
2012

GenomeRNAi version 9.0 released

This release features a dynamic genome browser for each gene, displaying gene, reagent and phenotype data via the DAS technology. Further we have added graphs indicating the score distribution and the position of individual scores on the gene details page. HeLa cell morphology images are available for the results reported by Fuchs et al.
27 June
2012

GenomeRNAi version 8.0 released

The database now contains 127 RNAi screens in human, and 164 screens in drosophila, of which 50 have been performed in vivo. We have added a Frequent hitters page, indicating which genes frequently show a phenotype. A DAS server allows the visualisation of phenotype data in a genome browser context.
30 March
2012

GenomeRNAi version 7.0 released

GenomeRNAi 7.0 is a data release providing newly curated phenotype data: The database now contains 124 RNAi screens in human, and 158 screens in drosophila, of which 50 have been performed in vivo.
12 January
2012

GenomeRNAi version 6.0 released

This release features new and updated phenotype data: The database now contains 96 RNAi screens in human, and 150 screens in drosophila (50 in vivo screens). You can link to the GenomeRNAi website using Ensembl, UniProt, Flybase, or CG identifiers; or GenomeRNAi stable IDs. Follow us on Twitter or Facebook. And do consider to submit your own data!
15 July
2011

GenomeRNAi version 5.0 released

This is a major release with new data, new functionality, and a completely new design. The database now contains phenotype data from 82 RNAi screens in Homo sapiens, and 136 screens in Drosophila melanogaster, including 33 in vivo screens. New annotation standards have been applied to newly curated publications (application of these standards to previously existing data is ongoing). Download options are now available.