Stable Id Screen title Pubmed Id Entrez Id Author-provided gene Id Assay Biomodel Reagent Id Score type Score cutoff Score Phenotype Comment GR00184-A-1 Self-renewal and pluripotency in human embryonic stem cells (1) 20953172 9411 NM_004815 POU5F1 protein expression hESC H1 M-008277-00 Z-score < -2 -1.64200578687528 none GR00141-A T cell chemotaxis 20473299 9411 NM_004815 Cell migration SupT1 np Chemotactic index > 1 standard deviation from plate mean by at least 2 shRNAs np none GR00149-A-1 Ciliogenesis and cilium length (1) 20393563 9411 9411 Smoothed protein expression htRPE 15221 Normalized percent inhibition > 1.5 OR < -1.5 standard deviations from mean 30.82 none GR00149-A-1 Ciliogenesis and cilium length (1) 20393563 9411 9411 Smoothed protein expression htRPE 15221 Normalized percent inhibition > 1.5 OR < -1.5 standard deviations from mean 7.62 none GR00149-A-1 Ciliogenesis and cilium length (1) 20393563 9411 9411 Smoothed protein expression htRPE 122573 Normalized percent inhibition > 1.5 OR < -1.5 standard deviations from mean -120.18 none GR00149-A-1 Ciliogenesis and cilium length (1) 20393563 9411 9411 Smoothed protein expression htRPE 122573 Normalized percent inhibition > 1.5 OR < -1.5 standard deviations from mean -91.18 none GR00149-A-1 Ciliogenesis and cilium length (1) 20393563 9411 9411 Smoothed protein expression htRPE 122574 Normalized percent inhibition > 1.5 OR < -1.5 standard deviations from mean -78.32 none GR00149-A-1 Ciliogenesis and cilium length (1) 20393563 9411 9411 Smoothed protein expression htRPE 122574 Normalized percent inhibition > 1.5 OR < -1.5 standard deviations from mean -89.11 none GR00149-A-1 Ciliogenesis and cilium length (1) 20393563 9411 9411 Smoothed protein expression htRPE 122575 Normalized percent inhibition > 1.5 OR < -1.5 standard deviations from mean -23.46 none GR00149-A-1 Ciliogenesis and cilium length (1) 20393563 9411 9411 Smoothed protein expression htRPE 122575 Normalized percent inhibition > 1.5 OR < -1.5 standard deviations from mean -1.93 none GR00149-A-1 Ciliogenesis and cilium length (1) 20393563 9411 9411 Smoothed protein expression htRPE np Normalized percent inhibition > 1.5 OR < -1.5 standard deviations from mean np none siRNA toxicity GR00196-A-1 TP53 interactions (1) 21642980 9411 ENSG00000137962 TP53 protein expression and viability HCT116 ( wildtype and TP53 knockout) np Complex, sp Complex criteria sp none GR00151-A-1 Homologous recombination DNA double-strand break repair (HR-DSBR) (1) 20613862 9411 ENSG00000137962 (HR-DSBR) DR-GFP reporter HeLa np Z-score < -2 OR > 2 1.445 none GR00180-A-1 Hepatitis C virus replication (1) 19286138 9411 9411 HCV replicon RNA copy number Huh7/Rep-Feo PL-50014 q-value Complex criteria 0.895 none GR00054-A Combinatorial effect with paclitaxel 17429401 9411 NM_004815 Viability (synthetic lethal) NCI-H1155 np Paclitaxel/control ratio Complex criteria 1.23 none GR00056-A Melanogenesis 19057677 9411 NM_004815 Melanin protein expression and viability MNT-1 np Normalized absorbance ratio > 2 standard deviations below mean 0.939 none GR00098-A-1 Cell division (1) 17994010 9411 ENSG00000137962 Cell number and DNA content HeLa ENSG00000137962 Complex, sp Complex criteria sp none GR00197-A-1 Human papillomavirus oncogene expression regulation (1) 20133580 9411 9411 HPV18 LCR reporter activity C33A/BE2/18LCR c4 M-008277-00 Z-score >= 2 -1.362299408 none GR00053-A Genome stability 19647519 9411 NM_004815 gamma-H2AX phosphorylation and DNA content HeLa np p-value Complex criteria sp none GR00221-A-1 Proliferation of cells with active beta-catenin (1) 20126544 9411 Viability MCF-7 TRCN0000002150 B-score < -1 -0.3 none GR00221-A-1 Proliferation of cells with active beta-catenin (1) 20126544 9411 Viability MCF-7 TRCN0000002152 B-score < -1 0 none GR00221-A-1 Proliferation of cells with active beta-catenin (1) 20126544 9411 Viability MCF-7 TRCN0000002153 B-score < -1 0.23 none GR00221-A-1 Proliferation of cells with active beta-catenin (1) 20126544 9411 Viability MCF-7 TRCN0000002149 B-score < -1 1.8 none GR00221-A-2 Proliferation of cells with active beta-catenin (2) 20126544 9411 Viability MDA-MB-231 TRCN0000002150 B-score < -1 -1.61 Decreased viability GR00221-A-2 Proliferation of cells with active beta-catenin (2) 20126544 9411 Viability MDA-MB-231 TRCN0000002152 B-score < -1 -0.8 none GR00221-A-2 Proliferation of cells with active beta-catenin (2) 20126544 9411 Viability MDA-MB-231 TRCN0000002153 B-score < -1 -0.54 none GR00221-A-2 Proliferation of cells with active beta-catenin (2) 20126544 9411 Viability MDA-MB-231 TRCN0000002149 B-score < -1 -0.03 none GR00221-A-3 Proliferation of cells with active beta-catenin (3) 20126544 9411 Viability MDA-MB-453 TRCN0000002153 B-score < -1 -0.38 none GR00221-A-3 Proliferation of cells with active beta-catenin (3) 20126544 9411 Viability MDA-MB-453 TRCN0000002152 B-score < -1 -0.02 none GR00221-A-3 Proliferation of cells with active beta-catenin (3) 20126544 9411 Viability MDA-MB-453 TRCN0000002149 B-score < -1 0.21 none GR00221-A-3 Proliferation of cells with active beta-catenin (3) 20126544 9411 Viability MDA-MB-453 TRCN0000002150 B-score < -1 0.67 none GR00221-A-4 Proliferation of cells with active beta-catenin (4) 20126544 9411 Viability T47D TRCN0000002151 B-score < -1 -1.75 Decreased viability GR00221-A-4 Proliferation of cells with active beta-catenin (4) 20126544 9411 Viability T47D TRCN0000002150 B-score < -1 -0.75 none GR00221-A-4 Proliferation of cells with active beta-catenin (4) 20126544 9411 Viability T47D TRCN0000002152 B-score < -1 -0.52 none GR00221-A-4 Proliferation of cells with active beta-catenin (4) 20126544 9411 Viability T47D TRCN0000002149 B-score < -1 -0.18 none GR00221-A-4 Proliferation of cells with active beta-catenin (4) 20126544 9411 Viability T47D TRCN0000002153 B-score < -1 0.49 none GR00236-A-1 Homologous recombination DNA double-strand break repair (HR-DSBR) (1) 22344029 9411 9411 (HR-DSBR) DR-GFP reporter and DNA content DR-U2OS M-008277-00 Relative HR ratio < ~0.4 OR > 1.88 1.05859044830465 none GR00240-S-1 TRAIL-induced apoptosis (1) 24442637 9411 NM_004815 Viability U251MG M-008277-00 Z-score > 4 0.02 none GR00240-S-2 TRAIL-induced apoptosis (2) 24442637 9411 NM_004815 Viability (synthetic lethal) U251MG M-008277-00 Differential score > 3.6 AND viability Z-score < 4 0.03 none Z-score 0.0535 GR00242-A-1 Selective autophagy regulation (1) 22020285 9411 NM_004815 Sindbis virus (SIN) capsid SIN-mCherry.capsid and autophagosome GFP–LC3 protein expression HeLa/GFP-LC3 np Z-score Complex criteria sp none GR00247-A-1 Regulation of FOXO1 nuclear localization (1) 21460183 9411 EGFP-FOXO1a protein expression and DNA content U2OS np Complex, sp Complex criteria sp none rank: 12186 GR00249-S Vaccinia virus (VACV) infection 23401514 9411 9411 Vaccinia virus VACV IHD-J/GFP protein expression and DNA content HeLa J-008277-05 Z-score >= 1 OR <= -1.5 0.6055 none number of cells compared to control (%): 90.34 GR00249-S Vaccinia virus (VACV) infection 23401514 9411 9411 Vaccinia virus VACV IHD-J/GFP protein expression and DNA content HeLa M-008277-01 Z-score >= 1 OR <= -1.5 0.33747 none number of cells compared to control (%): 81.12 GR00249-S Vaccinia virus (VACV) infection 23401514 9411 9411 Vaccinia virus VACV IHD-J/GFP protein expression and DNA content HeLa s484 Z-score >= 1 OR <= -1.5 1.08585 Increased vaccinia virus (VACV) infection number of cells compared to control (%): 94.55 GR00249-S Vaccinia virus (VACV) infection 23401514 9411 9411 Vaccinia virus VACV IHD-J/GFP protein expression and DNA content HeLa s485 Z-score >= 1 OR <= -1.5 0.40639 none number of cells compared to control (%): 63.79 GR00249-S Vaccinia virus (VACV) infection 23401514 9411 9411 Vaccinia virus VACV IHD-J/GFP protein expression and DNA content HeLa s486 Z-score >= 1 OR <= -1.5 -0.28305 none number of cells compared to control (%): 88.10 GR00253-A hepcidin regulation 24385536 9411 NM_004815 hepcidin::fluc mRNA expression Huh7 np Z-score >= 1.755 OR <= -1.389 0.146 none GR00255-A-1 Negative genetic interactions (1) 24104479 9411 9411 shRNA abundance HCT116 TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 differential Gene Activity Ranking Profile (dGARP) < -1.0 -0.69983104 none GR00255-A-2 Negative genetic interactions (2) 24104479 9411 9411 shRNA abundance HCT116 TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 differential Gene Activity Ranking Profile (dGARP) < -1.0 -0.880965252 none GR00255-A-3 Negative genetic interactions (3) 24104479 9411 9411 shRNA abundance HCT116 TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 differential Gene Activity Ranking Profile (dGARP) < -1.2 0.37792884 none GR00255-A-4 Negative genetic interactions (4) 24104479 9411 9411 shRNA abundance HCT116 TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 differential Gene Activity Ranking Profile (dGARP) < -1.2 -1.010927505 none GR00255-A-5 Negative genetic interactions (5) 24104479 9411 9411 shRNA abundance HCT116 TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 differential Gene Activity Ranking Profile (dGARP) < -0.8 0.795850337 none GR00057-A-1 Wnt/beta-catenin pathway regulation (1) 18621708 9411 NM_004815 Wnt pathway reporter HeLa M-008277-00 Z-score > 4 -0.53 none GR00057-A-2 Wnt/beta-catenin pathway regulation (2) 18621708 9411 NM_004815 Wnt pathway reporter HeLa M-008277-00 Complex, SP Complex criteria sp none GR00293-A Combinatorial effect with paclitaxel 24860162 9411 Viability HCC366 np Z-score < -2.5 1.315 none GR00300-A Combinatorial effect with RAF inhibitor PLX4720 23288408 9411 shRNA abundance A375 TRCN0000002150,TRCN0000002152,TRCN0000002151,TRCN0000002153,TRCN0000002149 Number of shRNAs ranked Top1000 > 2 0 none GR00303-A Clear cell renal cell carcinoma (ccRCC) survival regulation 22362593 9411 NM_004815 Proliferation and Viability VHL-deficient RCC4 np Z-score <= -3 -2.64 none GR00310-A-1 Sindbis virus (SINV) infection (1) 24367265 9411 9411 Sindbis virus (SINV) reporter U2OS np Z-score < -3 OR > 2 0.64 none GR00312-A NOD2 pathway regulation 23322906 9411 9411 NF-kappaB reporter HEK 293 np Normalized percent inhibition < -20 OR > 60; Inconclusive: < -20 and > 120 % viability OR > 60 and < 70 % viability 37.9 none 108,9% viability GR00313-A TNF-alpha pathway regulation 22733992 9411 NM_004815 NFkappaB pathway reporter HEK293T np Z-score <= -2.5 plus additional filters 0.09 none GR00318-A Huntingtin toxicity 23209424 9411 9411 Caspase 3/7 activity HEK293T np Sum of normalized caspase 3/7 activity mean and standard error < 0.683 1.284 none siRNA set: druggable genome GR00095-A p53 pathway components 15042092 9411 NM_004815 Proliferation BJ-TERT-tsLT fibroblasts np np np np none GR00343-S Lentiviral shRNA "Achilles Heel" screen 26058080 9411 9411 shRNA abundance K562 TRCN0000002152 Log2 ratio <= -2 (shRNA abundance <= 25%) -0.49249999999999794 none GR00343-S Lentiviral shRNA "Achilles Heel" screen 26058080 9411 9411 shRNA abundance K562 TRCN0000002151 Log2 ratio <= -2 (shRNA abundance <= 25%) -1.295 shRNA abundance <= 50% GR00343-S Lentiviral shRNA "Achilles Heel" screen 26058080 9411 9411 shRNA abundance K562 TRCN0000002149 Log2 ratio <= -2 (shRNA abundance <= 25%) 1.0624999999999982 none GR00343-S Lentiviral shRNA "Achilles Heel" screen 26058080 9411 9411 shRNA abundance K562 TRCN0000002150 Log2 ratio <= -2 (shRNA abundance <= 25%) -0.47250000000000014 none GR00123-A Combinatorial effect with nutlin-3 16474381 9411 NM_004815 Viability MCF-7 170872,170871,170873 log2 ratio np np none GR00351-A-1 Orthopoxvirus infection (1) 24516381 9411 Vaccinia virus (VACV-A4L) infection A549 np Number of replicates in which second best hairpin scored among Top 500 > 0 1 Resistant to vaccinia virus (VACV-A4L) infection GR00355-A PIP3-mediated epidermal growth factor (EGFR) endocytosis 24425787 9411 9411 Epidermal growth factor (EGFR) surface abundance HeLa Kyoto np Deviation score < -1 OR > 1 np none GR00366-A-1 Context-specific genetic dependencies (1) 25984343 9411 shRNA abundance 22RV1_PROSTATE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.666487397567307 none ARHGAP29_1_11111 GR00366-A-2 Context-specific genetic dependencies (2) 25984343 9411 shRNA abundance 697_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.707173839399328 none ARHGAP29_1_11111 GR00366-A-3 Context-specific genetic dependencies (3) 25984343 9411 shRNA abundance 786O_KIDNEY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.320953731470322 none ARHGAP29_1_11111 GR00366-A-4 Context-specific genetic dependencies (4) 25984343 9411 shRNA abundance A1207_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.219706453402621 none ARHGAP29_1_11111 GR00366-A-5 Context-specific genetic dependencies (5) 25984343 9411 shRNA abundance A172_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.252098246892041 none ARHGAP29_1_11111 GR00366-A-6 Context-specific genetic dependencies (6) 25984343 9411 shRNA abundance A204_SOFT_TISSUE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.293492611134464 none ARHGAP29_1_11111 GR00366-A-7 Context-specific genetic dependencies (7) 25984343 9411 shRNA abundance A2058_SKIN TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.15638913882024 none ARHGAP29_1_11111 GR00366-A-8 Context-specific genetic dependencies (8) 25984343 9411 shRNA abundance A549_LUNG TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.261139444784701 none ARHGAP29_1_11111 GR00366-A-9 Context-specific genetic dependencies (9) 25984343 9411 shRNA abundance A673_BONE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.965432824058586 none ARHGAP29_1_11111 GR00366-A-10 Context-specific genetic dependencies (10) 25984343 9411 shRNA abundance ACHN_KIDNEY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.138194824968587 none ARHGAP29_1_11111 GR00366-A-11 Context-specific genetic dependencies (11) 25984343 9411 shRNA abundance AGS_STOMACH TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.201034584466796 none ARHGAP29_1_11111 GR00366-A-12 Context-specific genetic dependencies (12) 25984343 9411 shRNA abundance AM38_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.5442309816523 none ARHGAP29_1_11111 GR00366-A-13 Context-specific genetic dependencies (13) 25984343 9411 shRNA abundance AML193_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 1.10250466763855 none ARHGAP29_1_11111 GR00366-A-14 Context-specific genetic dependencies (14) 25984343 9411 shRNA abundance ASPC1_PANCREAS TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.675814540031507 none ARHGAP29_1_11111 GR00366-A-15 Context-specific genetic dependencies (15) 25984343 9411 shRNA abundance BT20_BREAST TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.0568190012697112 none ARHGAP29_1_11111 GR00366-A-16 Context-specific genetic dependencies (16) 25984343 9411 shRNA abundance BT474_BREAST TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.130103238072724 none ARHGAP29_1_11111 GR00366-A-17 Context-specific genetic dependencies (17) 25984343 9411 shRNA abundance BXPC3_PANCREAS TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.172334703865709 none ARHGAP29_1_11111 GR00366-A-18 Context-specific genetic dependencies (18) 25984343 9411 shRNA abundance C2BBE1_LARGE_INTESTINE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.29663325187418 none ARHGAP29_1_11111 GR00366-A-19 Context-specific genetic dependencies (19) 25984343 9411 shRNA abundance C32_SKIN TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.0886010968396242 none ARHGAP29_1_11111 GR00366-A-20 Context-specific genetic dependencies (20) 25984343 9411 shRNA abundance CADOES1_BONE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.00139052938351012 none ARHGAP29_1_11111 GR00366-A-21 Context-specific genetic dependencies (21) 25984343 9411 shRNA abundance CAL120_BREAST TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.744781172352815 none ARHGAP29_1_11111 GR00366-A-22 Context-specific genetic dependencies (22) 25984343 9411 shRNA abundance CAL51_BREAST TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.303999898624164 none ARHGAP29_1_11111 GR00366-A-23 Context-specific genetic dependencies (23) 25984343 9411 shRNA abundance CALU1_LUNG TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.112876446273399 none ARHGAP29_1_11111 GR00366-A-24 Context-specific genetic dependencies (24) 25984343 9411 shRNA abundance CAOV3_OVARY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.0611159291472336 none ARHGAP29_1_11111 GR00366-A-25 Context-specific genetic dependencies (25) 25984343 9411 shRNA abundance CAOV4_OVARY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -1.08581506581968 Decreased shRNA abundance (Z-score < -2) ARHGAP29_1_11111 GR00366-A-26 Context-specific genetic dependencies (26) 25984343 9411 shRNA abundance CAS1_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.089775369404971 none ARHGAP29_1_11111 GR00366-A-27 Context-specific genetic dependencies (27) 25984343 9411 shRNA abundance CFPAC1_PANCREAS TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.527043230740466 none ARHGAP29_1_11111 GR00366-A-28 Context-specific genetic dependencies (28) 25984343 9411 shRNA abundance CH157MN_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.0550719758835337 none ARHGAP29_1_11111 GR00366-A-29 Context-specific genetic dependencies (29) 25984343 9411 shRNA abundance COLO205_LARGE_INTESTINE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.103189919057813 none ARHGAP29_1_11111 GR00366-A-30 Context-specific genetic dependencies (30) 25984343 9411 shRNA abundance COLO704_OVARY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.0216066918889765 none ARHGAP29_1_11111 GR00366-A-31 Context-specific genetic dependencies (31) 25984343 9411 shRNA abundance COLO741_SKIN TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.399986055578655 none ARHGAP29_1_11111 GR00366-A-32 Context-specific genetic dependencies (32) 25984343 9411 shRNA abundance COLO783_SKIN TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.292739271887735 none ARHGAP29_1_11111 GR00366-A-33 Context-specific genetic dependencies (33) 25984343 9411 shRNA abundance CORL23_LUNG TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.0695199915208657 none ARHGAP29_1_11111 GR00366-A-34 Context-specific genetic dependencies (34) 25984343 9411 shRNA abundance COV362_OVARY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -1.09377173390617 Decreased shRNA abundance (Z-score < -2) ARHGAP29_1_11111 GR00366-A-35 Context-specific genetic dependencies (35) 25984343 9411 shRNA abundance COV434_OVARY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.141052009632369 none ARHGAP29_1_11111 GR00366-A-36 Context-specific genetic dependencies (36) 25984343 9411 shRNA abundance COV504_OVARY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.2063087181924 none ARHGAP29_1_11111 GR00366-A-37 Context-specific genetic dependencies (37) 25984343 9411 shRNA abundance COV644_OVARY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.569992859945001 none ARHGAP29_1_11111 GR00366-A-38 Context-specific genetic dependencies (38) 25984343 9411 shRNA abundance DBTRG05MG_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.0727878002520058 none ARHGAP29_1_11111 GR00366-A-39 Context-specific genetic dependencies (39) 25984343 9411 shRNA abundance DKMG_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.190057590107693 none ARHGAP29_1_11111 GR00366-A-40 Context-specific genetic dependencies (40) 25984343 9411 shRNA abundance DLD1_LARGE_INTESTINE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.580416217220603 none ARHGAP29_1_11111 GR00366-A-41 Context-specific genetic dependencies (41) 25984343 9411 shRNA abundance EFE184_ENDOMETRIUM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.502227110274029 none ARHGAP29_1_11111 GR00366-A-42 Context-specific genetic dependencies (42) 25984343 9411 shRNA abundance EFM19_BREAST TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.799986743223634 none ARHGAP29_1_11111 GR00366-A-43 Context-specific genetic dependencies (43) 25984343 9411 shRNA abundance EFO21_OVARY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -1.36599058634705 Decreased shRNA abundance (Z-score < -2) ARHGAP29_1_11111 GR00366-A-44 Context-specific genetic dependencies (44) 25984343 9411 shRNA abundance EFO27_OVARY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.194349621398909 none ARHGAP29_1_11111 GR00366-A-45 Context-specific genetic dependencies (45) 25984343 9411 shRNA abundance EW8_BONE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.0536803618611409 none ARHGAP29_1_11111 GR00366-A-46 Context-specific genetic dependencies (46) 25984343 9411 shRNA abundance EWS502_BONE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.650042303318096 none ARHGAP29_1_11111 GR00366-A-47 Context-specific genetic dependencies (47) 25984343 9411 shRNA abundance F36P_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 1.80586348222779 Increased shRNA abundance (Z-score > 2) ARHGAP29_1_11111 GR00366-A-48 Context-specific genetic dependencies (48) 25984343 9411 shRNA abundance GB1_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.00269005352863324 none ARHGAP29_1_11111 GR00366-A-49 Context-specific genetic dependencies (49) 25984343 9411 shRNA abundance GP2D_LARGE_INTESTINE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.604354990550384 none ARHGAP29_1_11111 GR00366-A-50 Context-specific genetic dependencies (50) 25984343 9411 shRNA abundance HCC1187_BREAST TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.247697820638102 none ARHGAP29_1_11111 GR00366-A-51 Context-specific genetic dependencies (51) 25984343 9411 shRNA abundance HCC1395_BREAST TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.41036304177498 none ARHGAP29_1_11111 GR00366-A-52 Context-specific genetic dependencies (52) 25984343 9411 shRNA abundance HCC1954_BREAST TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.996841842147467 none ARHGAP29_1_11111 GR00366-A-53 Context-specific genetic dependencies (53) 25984343 9411 shRNA abundance HCC2218_BREAST TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.489791592870195 none ARHGAP29_1_11111 GR00366-A-54 Context-specific genetic dependencies (54) 25984343 9411 shRNA abundance HCC2814_LUNG TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.198515170000327 none ARHGAP29_1_11111 GR00366-A-55 Context-specific genetic dependencies (55) 25984343 9411 shRNA abundance HCC364_LUNG TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.220714895283828 none ARHGAP29_1_11111 GR00366-A-56 Context-specific genetic dependencies (56) 25984343 9411 shRNA abundance HCC44_LUNG TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.0338760615841162 none ARHGAP29_1_11111 GR00366-A-57 Context-specific genetic dependencies (57) 25984343 9411 shRNA abundance HCC70_BREAST TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.534159445343905 none ARHGAP29_1_11111 GR00366-A-58 Context-specific genetic dependencies (58) 25984343 9411 shRNA abundance HCC827GR5_LUNG TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.0834003907225053 none ARHGAP29_1_11111 GR00366-A-59 Context-specific genetic dependencies (59) 25984343 9411 shRNA abundance HCC827_LUNG TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.1989106022542 none ARHGAP29_1_11111 GR00366-A-60 Context-specific genetic dependencies (60) 25984343 9411 shRNA abundance HCT116_LARGE_INTESTINE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.0914478909007656 none ARHGAP29_1_11111 GR00366-A-61 Context-specific genetic dependencies (61) 25984343 9411 shRNA abundance HEC1A_ENDOMETRIUM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.419770819085412 none ARHGAP29_1_11111 GR00366-A-62 Context-specific genetic dependencies (62) 25984343 9411 shRNA abundance HEYA8_OVARY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.428373311414828 none ARHGAP29_1_11111 GR00366-A-63 Context-specific genetic dependencies (63) 25984343 9411 shRNA abundance HL60_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.205842304261375 none ARHGAP29_1_11111 GR00366-A-64 Context-specific genetic dependencies (64) 25984343 9411 shRNA abundance HLF_LIVER TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.615668400300485 none ARHGAP29_1_11111 GR00366-A-65 Context-specific genetic dependencies (65) 25984343 9411 shRNA abundance HNT34_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.323928647691741 none ARHGAP29_1_11111 GR00366-A-66 Context-specific genetic dependencies (66) 25984343 9411 shRNA abundance HPAC_PANCREAS TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.9272317768093 none ARHGAP29_1_11111 GR00366-A-67 Context-specific genetic dependencies (67) 25984343 9411 shRNA abundance HPAFII_PANCREAS TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.173131259281745 none ARHGAP29_1_11111 GR00366-A-68 Context-specific genetic dependencies (68) 25984343 9411 shRNA abundance HS683_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.309198015128385 none ARHGAP29_1_11111 GR00366-A-69 Context-specific genetic dependencies (69) 25984343 9411 shRNA abundance HS766T_PANCREAS TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.649326918117049 none ARHGAP29_1_11111 GR00366-A-70 Context-specific genetic dependencies (70) 25984343 9411 shRNA abundance HS944T_SKIN TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.927089646082388 none ARHGAP29_1_11111 GR00366-A-71 Context-specific genetic dependencies (71) 25984343 9411 shRNA abundance HT1197_URINARY_TRACT TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.268806821182761 none ARHGAP29_1_11111 GR00366-A-72 Context-specific genetic dependencies (72) 25984343 9411 shRNA abundance HT29_LARGE_INTESTINE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.0673442132764011 none ARHGAP29_1_11111 GR00366-A-73 Context-specific genetic dependencies (73) 25984343 9411 shRNA abundance HT55_LARGE_INTESTINE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.391366719616817 none ARHGAP29_1_11111 GR00366-A-74 Context-specific genetic dependencies (74) 25984343 9411 shRNA abundance HUG1N_STOMACH TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.0319907626408393 none ARHGAP29_1_11111 GR00366-A-75 Context-specific genetic dependencies (75) 25984343 9411 shRNA abundance HUTU80_SMALL_INTESTINE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.115860256093287 none ARHGAP29_1_11111 GR00366-A-76 Context-specific genetic dependencies (76) 25984343 9411 shRNA abundance IGR39_SKIN TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.506218692357333 none ARHGAP29_1_11111 GR00366-A-77 Context-specific genetic dependencies (77) 25984343 9411 shRNA abundance IGROV1_OVARY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.540353203852182 none ARHGAP29_1_11111 GR00366-A-78 Context-specific genetic dependencies (78) 25984343 9411 shRNA abundance IOMMLEE_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.932778462451914 none ARHGAP29_1_11111 GR00366-A-79 Context-specific genetic dependencies (79) 25984343 9411 shRNA abundance JHESOAD1_OESOPHAGUS TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.283610413768091 none ARHGAP29_1_11111 GR00366-A-80 Context-specific genetic dependencies (80) 25984343 9411 shRNA abundance JHOC5_OVARY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.268590924137721 none ARHGAP29_1_11111 GR00366-A-81 Context-specific genetic dependencies (81) 25984343 9411 shRNA abundance JHOM1_OVARY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.736099980597954 none ARHGAP29_1_11111 GR00366-A-82 Context-specific genetic dependencies (82) 25984343 9411 shRNA abundance JJN3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 1.37439435226554 Increased shRNA abundance (Z-score > 2) ARHGAP29_1_11111 GR00366-A-83 Context-specific genetic dependencies (83) 25984343 9411 shRNA abundance K562_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.199109683145992 none ARHGAP29_1_11111 GR00366-A-84 Context-specific genetic dependencies (84) 25984343 9411 shRNA abundance KALS1_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.267437804905585 none ARHGAP29_1_11111 GR00366-A-85 Context-specific genetic dependencies (85) 25984343 9411 shRNA abundance KASUMI1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.223704149764874 none ARHGAP29_1_11111 GR00366-A-86 Context-specific genetic dependencies (86) 25984343 9411 shRNA abundance KM12_LARGE_INTESTINE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.446465098316117 none ARHGAP29_1_11111 GR00366-A-87 Context-specific genetic dependencies (87) 25984343 9411 shRNA abundance KMS12BM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.652259553904043 none ARHGAP29_1_11111 GR00366-A-88 Context-specific genetic dependencies (88) 25984343 9411 shRNA abundance KNS60_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.642616476299906 none ARHGAP29_1_11111 GR00366-A-89 Context-specific genetic dependencies (89) 25984343 9411 shRNA abundance KNS81_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.140600076785821 none ARHGAP29_1_11111 GR00366-A-90 Context-specific genetic dependencies (90) 25984343 9411 shRNA abundance KP1NL_PANCREAS TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.142383077810082 none ARHGAP29_1_11111 GR00366-A-91 Context-specific genetic dependencies (91) 25984343 9411 shRNA abundance KP2_PANCREAS TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 1.28206805351658 Increased shRNA abundance (Z-score > 2) ARHGAP29_1_11111 GR00366-A-92 Context-specific genetic dependencies (92) 25984343 9411 shRNA abundance KP4_PANCREAS TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.298305801013234 none ARHGAP29_1_11111 GR00366-A-93 Context-specific genetic dependencies (93) 25984343 9411 shRNA abundance KURAMOCHI_OVARY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -1.12968074933118 Decreased shRNA abundance (Z-score < -2) ARHGAP29_1_11111 GR00366-A-94 Context-specific genetic dependencies (94) 25984343 9411 shRNA abundance KYSE150_OESOPHAGUS TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.0727623040556662 none ARHGAP29_1_11111 GR00366-A-95 Context-specific genetic dependencies (95) 25984343 9411 shRNA abundance KYSE30_OESOPHAGUS TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.0806785394194399 none ARHGAP29_1_11111 GR00366-A-96 Context-specific genetic dependencies (96) 25984343 9411 shRNA abundance KYSE450_OESOPHAGUS TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.225200889458306 none ARHGAP29_1_11111 GR00366-A-97 Context-specific genetic dependencies (97) 25984343 9411 shRNA abundance KYSE510_OESOPHAGUS TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.321344096339573 none ARHGAP29_1_11111 GR00366-A-98 Context-specific genetic dependencies (98) 25984343 9411 shRNA abundance L33_PANCREAS TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.501141541420167 none ARHGAP29_1_11111 GR00366-A-99 Context-specific genetic dependencies (99) 25984343 9411 shRNA abundance L363_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.854861470727008 none ARHGAP29_1_11111 GR00366-A-100 Context-specific genetic dependencies (100) 25984343 9411 shRNA abundance LAMA84_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.191431576038036 none ARHGAP29_1_11111 GR00366-A-101 Context-specific genetic dependencies (101) 25984343 9411 shRNA abundance LK2_LUNG TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.447604480023696 none ARHGAP29_1_11111 GR00366-A-102 Context-specific genetic dependencies (102) 25984343 9411 shRNA abundance LN215_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.263772537772557 none ARHGAP29_1_11111 GR00366-A-103 Context-specific genetic dependencies (103) 25984343 9411 shRNA abundance LN229_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.174429536804536 none ARHGAP29_1_11111 GR00366-A-104 Context-specific genetic dependencies (104) 25984343 9411 shRNA abundance LN235_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.00749706194871478 none ARHGAP29_1_11111 GR00366-A-105 Context-specific genetic dependencies (105) 25984343 9411 shRNA abundance LN319_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -1.46087279061164 Decreased shRNA abundance (Z-score < -2) ARHGAP29_1_11111 GR00366-A-106 Context-specific genetic dependencies (106) 25984343 9411 shRNA abundance LN340_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.61981726491965 none ARHGAP29_1_11111 GR00366-A-107 Context-specific genetic dependencies (107) 25984343 9411 shRNA abundance LN382_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.223876117746009 none ARHGAP29_1_11111 GR00366-A-108 Context-specific genetic dependencies (108) 25984343 9411 shRNA abundance LN428_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.50354581691489 none ARHGAP29_1_11111 GR00366-A-109 Context-specific genetic dependencies (109) 25984343 9411 shRNA abundance LN443_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.120090105075725 none ARHGAP29_1_11111 GR00366-A-110 Context-specific genetic dependencies (110) 25984343 9411 shRNA abundance LN464_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.140403803285192 none ARHGAP29_1_11111 GR00366-A-111 Context-specific genetic dependencies (111) 25984343 9411 shRNA abundance LNZ308_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.614535255403243 none ARHGAP29_1_11111 GR00366-A-112 Context-specific genetic dependencies (112) 25984343 9411 shRNA abundance LOVO_LARGE_INTESTINE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.49530618080081 none ARHGAP29_1_11111 GR00366-A-113 Context-specific genetic dependencies (113) 25984343 9411 shRNA abundance LS411N_LARGE_INTESTINE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.522744724764251 none ARHGAP29_1_11111 GR00366-A-114 Context-specific genetic dependencies (114) 25984343 9411 shRNA abundance LS513_LARGE_INTESTINE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.126227754407893 none ARHGAP29_1_11111 GR00366-A-115 Context-specific genetic dependencies (115) 25984343 9411 shRNA abundance MCF7_BREAST TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.189607735564935 none ARHGAP29_1_11111 GR00366-A-116 Context-specific genetic dependencies (116) 25984343 9411 shRNA abundance MDAMB453_BREAST TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 1.3434919068412 Increased shRNA abundance (Z-score > 2) ARHGAP29_1_11111 GR00366-A-117 Context-specific genetic dependencies (117) 25984343 9411 shRNA abundance MIAPACA2_PANCREAS TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.211992566801822 none ARHGAP29_1_11111 GR00366-A-118 Context-specific genetic dependencies (118) 25984343 9411 shRNA abundance MKN7_STOMACH TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.152989592652156 none ARHGAP29_1_11111 GR00366-A-119 Context-specific genetic dependencies (119) 25984343 9411 shRNA abundance MM1S_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.991588327400719 none ARHGAP29_1_11111 GR00366-A-120 Context-specific genetic dependencies (120) 25984343 9411 shRNA abundance MOLM13_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.531014951841589 none ARHGAP29_1_11111 GR00366-A-121 Context-specific genetic dependencies (121) 25984343 9411 shRNA abundance MONOMAC1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.502575815894345 none ARHGAP29_1_11111 GR00366-A-122 Context-specific genetic dependencies (122) 25984343 9411 shRNA abundance MONOMAC6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.0562498339158714 none ARHGAP29_1_11111 GR00366-A-123 Context-specific genetic dependencies (123) 25984343 9411 shRNA abundance MV411_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.423166278416573 none ARHGAP29_1_11111 GR00366-A-124 Context-specific genetic dependencies (124) 25984343 9411 shRNA abundance NALM6_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.0726780030435019 none ARHGAP29_1_11111 GR00366-A-125 Context-specific genetic dependencies (125) 25984343 9411 shRNA abundance NB4_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.554442345092876 none ARHGAP29_1_11111 GR00366-A-126 Context-specific genetic dependencies (126) 25984343 9411 shRNA abundance NCIH1299_LUNG TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.235816322914536 none ARHGAP29_1_11111 GR00366-A-127 Context-specific genetic dependencies (127) 25984343 9411 shRNA abundance NCIH1437_LUNG TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.652342822121746 none ARHGAP29_1_11111 GR00366-A-128 Context-specific genetic dependencies (128) 25984343 9411 shRNA abundance NCIH1650_LUNG TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.0256363370531946 none ARHGAP29_1_11111 GR00366-A-129 Context-specific genetic dependencies (129) 25984343 9411 shRNA abundance NCIH1792_LUNG TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.341083171593763 none ARHGAP29_1_11111 GR00366-A-130 Context-specific genetic dependencies (130) 25984343 9411 shRNA abundance NCIH196_LUNG TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.493904462148501 none ARHGAP29_1_11111 GR00366-A-131 Context-specific genetic dependencies (131) 25984343 9411 shRNA abundance NCIH1975_LUNG TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.971655949317328 none ARHGAP29_1_11111 GR00366-A-132 Context-specific genetic dependencies (132) 25984343 9411 shRNA abundance NCIH2052_PLEURA TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.0385503507982641 none ARHGAP29_1_11111 GR00366-A-133 Context-specific genetic dependencies (133) 25984343 9411 shRNA abundance NCIH2122_LUNG TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.3351102148746 none ARHGAP29_1_11111 GR00366-A-134 Context-specific genetic dependencies (134) 25984343 9411 shRNA abundance NCIH2171_LUNG TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.0566079385806429 none ARHGAP29_1_11111 GR00366-A-135 Context-specific genetic dependencies (135) 25984343 9411 shRNA abundance NCIH23_LUNG TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.395878958603112 none ARHGAP29_1_11111 GR00366-A-136 Context-specific genetic dependencies (136) 25984343 9411 shRNA abundance NCIH2452_PLEURA TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.342224293543249 none ARHGAP29_1_11111 GR00366-A-137 Context-specific genetic dependencies (137) 25984343 9411 shRNA abundance NCIH441_LUNG TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.56979724176099 none ARHGAP29_1_11111 GR00366-A-138 Context-specific genetic dependencies (138) 25984343 9411 shRNA abundance NCIH508_LARGE_INTESTINE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.684214240738023 none ARHGAP29_1_11111 GR00366-A-139 Context-specific genetic dependencies (139) 25984343 9411 shRNA abundance NCIH660_PROSTATE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 1.0166170125734 none ARHGAP29_1_11111 GR00366-A-140 Context-specific genetic dependencies (140) 25984343 9411 shRNA abundance NCIH661_LUNG TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.136861560963443 none ARHGAP29_1_11111 GR00366-A-141 Context-specific genetic dependencies (141) 25984343 9411 shRNA abundance NCIH716_LARGE_INTESTINE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.450658901231797 none ARHGAP29_1_11111 GR00366-A-142 Context-specific genetic dependencies (142) 25984343 9411 shRNA abundance NCIH838_LUNG TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.965974949651238 none ARHGAP29_1_11111 GR00366-A-143 Context-specific genetic dependencies (143) 25984343 9411 shRNA abundance NCIN87_STOMACH TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.158439518871528 none ARHGAP29_1_11111 GR00366-A-144 Context-specific genetic dependencies (144) 25984343 9411 shRNA abundance NIHOVCAR3_OVARY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.599838821490821 none ARHGAP29_1_11111 GR00366-A-145 Context-specific genetic dependencies (145) 25984343 9411 shRNA abundance NOMO1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 2.01437029881152 Increased shRNA abundance (Z-score > 2) ARHGAP29_1_11111 GR00366-A-146 Context-specific genetic dependencies (146) 25984343 9411 shRNA abundance OAW42_OVARY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.129534135607473 none ARHGAP29_1_11111 GR00366-A-147 Context-specific genetic dependencies (147) 25984343 9411 shRNA abundance OCIAML2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.556072706811711 none ARHGAP29_1_11111 GR00366-A-148 Context-specific genetic dependencies (148) 25984343 9411 shRNA abundance OCIAML3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.220187479951755 none ARHGAP29_1_11111 GR00366-A-149 Context-specific genetic dependencies (149) 25984343 9411 shRNA abundance OCIAML5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.371254208885804 none ARHGAP29_1_11111 GR00366-A-150 Context-specific genetic dependencies (150) 25984343 9411 shRNA abundance OE33_OESOPHAGUS TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.933209669345185 none ARHGAP29_1_11111 GR00366-A-151 Context-specific genetic dependencies (151) 25984343 9411 shRNA abundance OELE_OVARY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.463858503384244 none ARHGAP29_1_11111 GR00366-A-152 Context-specific genetic dependencies (152) 25984343 9411 shRNA abundance OPM2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.52097125588302 none ARHGAP29_1_11111 GR00366-A-153 Context-specific genetic dependencies (153) 25984343 9411 shRNA abundance OV7_OVARY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 1.14693064828894 none ARHGAP29_1_11111 GR00366-A-154 Context-specific genetic dependencies (154) 25984343 9411 shRNA abundance OV90_OVARY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.760651274849551 none ARHGAP29_1_11111 GR00366-A-155 Context-specific genetic dependencies (155) 25984343 9411 shRNA abundance OVCAR4_OVARY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.125721061443822 none ARHGAP29_1_11111 GR00366-A-156 Context-specific genetic dependencies (156) 25984343 9411 shRNA abundance OVCAR8_OVARY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.11601447465296 none ARHGAP29_1_11111 GR00366-A-157 Context-specific genetic dependencies (157) 25984343 9411 shRNA abundance OVISE_OVARY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.628337050911258 none ARHGAP29_1_11111 GR00366-A-158 Context-specific genetic dependencies (158) 25984343 9411 shRNA abundance PANC0327_PANCREAS TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.0225780916816524 none ARHGAP29_1_11111 GR00366-A-159 Context-specific genetic dependencies (159) 25984343 9411 shRNA abundance PANC0813_PANCREAS TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.161323992891131 none ARHGAP29_1_11111 GR00366-A-160 Context-specific genetic dependencies (160) 25984343 9411 shRNA abundance PANC1005_PANCREAS TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.598639875205708 none ARHGAP29_1_11111 GR00366-A-161 Context-specific genetic dependencies (161) 25984343 9411 shRNA abundance PLB985_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.577590097504528 none ARHGAP29_1_11111 GR00366-A-162 Context-specific genetic dependencies (162) 25984343 9411 shRNA abundance PSN1_PANCREAS TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.309929637316756 none ARHGAP29_1_11111 GR00366-A-163 Context-specific genetic dependencies (163) 25984343 9411 shRNA abundance QGP1_PANCREAS TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.34112817298788 none ARHGAP29_1_11111 GR00366-A-164 Context-specific genetic dependencies (164) 25984343 9411 shRNA abundance REH_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.538164538237748 none ARHGAP29_1_11111 GR00366-A-165 Context-specific genetic dependencies (165) 25984343 9411 shRNA abundance RKN_SOFT_TISSUE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.00641872191442353 none ARHGAP29_1_11111 GR00366-A-166 Context-specific genetic dependencies (166) 25984343 9411 shRNA abundance RKO_LARGE_INTESTINE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.554858429245006 none ARHGAP29_1_11111 GR00366-A-167 Context-specific genetic dependencies (167) 25984343 9411 shRNA abundance RMGI_OVARY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.366847187104897 none ARHGAP29_1_11111 GR00366-A-168 Context-specific genetic dependencies (168) 25984343 9411 shRNA abundance RMUGS_OVARY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.191008748763678 none ARHGAP29_1_11111 GR00366-A-169 Context-specific genetic dependencies (169) 25984343 9411 shRNA abundance RS411_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.0934545737950454 none ARHGAP29_1_11111 GR00366-A-170 Context-specific genetic dependencies (170) 25984343 9411 shRNA abundance RT112_URINARY_TRACT TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.297743893605283 none ARHGAP29_1_11111 GR00366-A-171 Context-specific genetic dependencies (171) 25984343 9411 shRNA abundance SEM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.230438113616783 none ARHGAP29_1_11111 GR00366-A-172 Context-specific genetic dependencies (172) 25984343 9411 shRNA abundance SF126_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.036816146773528 none ARHGAP29_1_11111 GR00366-A-173 Context-specific genetic dependencies (173) 25984343 9411 shRNA abundance SF172_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -1.00176231346122 none ARHGAP29_1_11111 GR00366-A-174 Context-specific genetic dependencies (174) 25984343 9411 shRNA abundance SF295_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.278997762380318 none ARHGAP29_1_11111 GR00366-A-175 Context-specific genetic dependencies (175) 25984343 9411 shRNA abundance SF767_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.0836464727177925 none ARHGAP29_1_11111 GR00366-A-176 Context-specific genetic dependencies (176) 25984343 9411 shRNA abundance SJSA1_BONE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.504209980211601 none ARHGAP29_1_11111 GR00366-A-177 Context-specific genetic dependencies (177) 25984343 9411 shRNA abundance SKCO1_LARGE_INTESTINE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.555208785476309 none ARHGAP29_1_11111 GR00366-A-178 Context-specific genetic dependencies (178) 25984343 9411 shRNA abundance SKMEL5_SKIN TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.536976143301959 none ARHGAP29_1_11111 GR00366-A-179 Context-specific genetic dependencies (179) 25984343 9411 shRNA abundance SKMM2_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.0846395692975651 none ARHGAP29_1_11111 GR00366-A-180 Context-specific genetic dependencies (180) 25984343 9411 shRNA abundance SKNO1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.401536163248971 none ARHGAP29_1_11111 GR00366-A-181 Context-specific genetic dependencies (181) 25984343 9411 shRNA abundance SKOV3_OVARY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 2.68098254794408 Increased shRNA abundance (Z-score > 2) ARHGAP29_1_11111 GR00366-A-182 Context-specific genetic dependencies (182) 25984343 9411 shRNA abundance SKRC20_KIDNEY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.555415244856082 none ARHGAP29_1_11111 GR00366-A-183 Context-specific genetic dependencies (183) 25984343 9411 shRNA abundance SLR20_KIDNEY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.0738418141625547 none ARHGAP29_1_11111 GR00366-A-184 Context-specific genetic dependencies (184) 25984343 9411 shRNA abundance SLR21_KIDNEY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.796968645886602 none ARHGAP29_1_11111 GR00366-A-185 Context-specific genetic dependencies (185) 25984343 9411 shRNA abundance SLR23_KIDNEY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.182510071566129 none ARHGAP29_1_11111 GR00366-A-186 Context-specific genetic dependencies (186) 25984343 9411 shRNA abundance SLR24_KIDNEY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 1.30051588885583 Increased shRNA abundance (Z-score > 2) ARHGAP29_1_11111 GR00366-A-187 Context-specific genetic dependencies (187) 25984343 9411 shRNA abundance SLR25_KIDNEY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.092099310361154 none ARHGAP29_1_11111 GR00366-A-188 Context-specific genetic dependencies (188) 25984343 9411 shRNA abundance SLR26_KIDNEY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.608202594535307 none ARHGAP29_1_11111 GR00366-A-189 Context-specific genetic dependencies (189) 25984343 9411 shRNA abundance SNU1105_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.0751432223473694 none ARHGAP29_1_11111 GR00366-A-190 Context-specific genetic dependencies (190) 25984343 9411 shRNA abundance SNU840_OVARY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.85720412794364 none ARHGAP29_1_11111 GR00366-A-191 Context-specific genetic dependencies (191) 25984343 9411 shRNA abundance SNUC1_LARGE_INTESTINE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.00359255403081685 none ARHGAP29_1_11111 GR00366-A-192 Context-specific genetic dependencies (192) 25984343 9411 shRNA abundance SNUC2A_LARGE_INTESTINE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.215488785202672 none ARHGAP29_1_11111 GR00366-A-193 Context-specific genetic dependencies (193) 25984343 9411 shRNA abundance SU8686_PANCREAS TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.439734778254776 none ARHGAP29_1_11111 GR00366-A-194 Context-specific genetic dependencies (194) 25984343 9411 shRNA abundance SW1417_LARGE_INTESTINE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.14095462117305 none ARHGAP29_1_11111 GR00366-A-195 Context-specific genetic dependencies (195) 25984343 9411 shRNA abundance SW1783_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.318524665411391 none ARHGAP29_1_11111 GR00366-A-196 Context-specific genetic dependencies (196) 25984343 9411 shRNA abundance SW480_LARGE_INTESTINE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.474149119118524 none ARHGAP29_1_11111 GR00366-A-197 Context-specific genetic dependencies (197) 25984343 9411 shRNA abundance SW48_LARGE_INTESTINE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.105388657824445 none ARHGAP29_1_11111 GR00366-A-198 Context-specific genetic dependencies (198) 25984343 9411 shRNA abundance T98G_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.0576491271053838 none ARHGAP29_1_11111 GR00366-A-199 Context-specific genetic dependencies (199) 25984343 9411 shRNA abundance TC71_BONE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.248517705391313 none ARHGAP29_1_11111 GR00366-A-200 Context-specific genetic dependencies (200) 25984343 9411 shRNA abundance TCCSUP_URINARY_TRACT TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.56731031395636 none ARHGAP29_1_11111 GR00366-A-201 Context-specific genetic dependencies (201) 25984343 9411 shRNA abundance TE10_OESOPHAGUS TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.393077654763568 none ARHGAP29_1_11111 GR00366-A-202 Context-specific genetic dependencies (202) 25984343 9411 shRNA abundance TE15_OESOPHAGUS TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.392263549904369 none ARHGAP29_1_11111 GR00366-A-203 Context-specific genetic dependencies (203) 25984343 9411 shRNA abundance TE9_OESOPHAGUS TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.235315820583589 none ARHGAP29_1_11111 GR00366-A-204 Context-specific genetic dependencies (204) 25984343 9411 shRNA abundance THP1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.443787354102826 none ARHGAP29_1_11111 GR00366-A-205 Context-specific genetic dependencies (205) 25984343 9411 shRNA abundance TOV112D_OVARY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.886880889861083 none ARHGAP29_1_11111 GR00366-A-206 Context-specific genetic dependencies (206) 25984343 9411 shRNA abundance TOV21G_OVARY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.599811455939577 none ARHGAP29_1_11111 GR00366-A-207 Context-specific genetic dependencies (207) 25984343 9411 shRNA abundance TT_OESOPHAGUS TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.360268286933078 none ARHGAP29_1_11111 GR00366-A-208 Context-specific genetic dependencies (208) 25984343 9411 shRNA abundance TYKNU_OVARY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.327382417244493 none ARHGAP29_1_11111 GR00366-A-209 Context-specific genetic dependencies (209) 25984343 9411 shRNA abundance U178_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 1.1655578382369 none ARHGAP29_1_11111 GR00366-A-210 Context-specific genetic dependencies (210) 25984343 9411 shRNA abundance U251MG_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.082106953232338 none ARHGAP29_1_11111 GR00366-A-211 Context-specific genetic dependencies (211) 25984343 9411 shRNA abundance U343_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.239173119876984 none ARHGAP29_1_11111 GR00366-A-212 Context-specific genetic dependencies (212) 25984343 9411 shRNA abundance U87MG_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 0.392318507856238 none ARHGAP29_1_11111 GR00366-A-213 Context-specific genetic dependencies (213) 25984343 9411 shRNA abundance UOK101_KIDNEY TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) 1.04424135945761 none ARHGAP29_1_11111 GR00366-A-214 Context-specific genetic dependencies (214) 25984343 9411 shRNA abundance VCAP_PROSTATE TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.927087295904659 none ARHGAP29_1_11111 GR00366-A-215 Context-specific genetic dependencies (215) 25984343 9411 shRNA abundance YKG1_CENTRAL_NERVOUS_SYSTEM TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.233952984709691 none ARHGAP29_1_11111 GR00366-A-216 Context-specific genetic dependencies (216) 25984343 9411 shRNA abundance ZR7530_BREAST TRCN0000002149,TRCN0000002150,TRCN0000002151,TRCN0000002152,TRCN0000002153 Fold change np (default cutoff applied: Z-score > 2 OR < -2) -0.114227085588716 none ARHGAP29_1_11111 GR00368-A Combinatorial effect with E-Cadherin 25777964 9411 9411 Viability (synthetic lethal) MCF10A [object Object] CDH1(-/-)/wt viability ratio <=85% [wt viability >= 50%] 0.62 Decreased viability ratio wt viability: 0,64 GR00369-A Combinatorial effect with FBW7 26354767 9411 9411 shRNA abundance HCT116 [object Object] Gene Activity Ranking Profile (GARP) Difference of FBW7(-/-) and wt GARP scores that fell >3 SD away from the mean -0.06999999999999998 none GR00376-A-1 Mitigators of SS1P-induced immunotoxicity 25713356 9411 9411 Viability KB cells [object Object] RSA P-value <0.001 0.346602763 none GR00376-A-2 Sensitizers of SS1P-induced immunotoxicity 25713356 9411 9411 Viability KB cells [object Object] RSA P-value <0.001 0.050336664 none GR00378-A Poliovirus vaccine production 26581994 9411 Infection with Attenuated Poliovirus HEp-2C [object Object] Z-score >=3 -1.130072339 none GR00381-A-1 Regulation of mammary epithelial cell growth (1) 25572802 9411 NM_004815 Viability 184-hTERT-L9 (mammary epithelial cells) [object Object] Percent growth < 25 % AND p-value < 0.05 36.884 none GR00386-A-1 NOD2 stimulation by MDP 25170077 9411 9411 Viability HEK293 stably expressing NOD2 [object Object] Percentage growth Decreased: <70, increased: >120 118.696644271727 none GR00386-A-2 MDP-induced IL-8 secretion 25170077 9411 9411 IL-8 secretion HEK293 stably expressing NOD2 [object Object] Percent inhibition of IL-8 secretion Increased: <-300, Decreased: >60 -55.5 none GR00400-S-1 Combinatorial effect with vorinostat (1) 25977774 9411 9411 Caspase 3/7 activity HCT116 (Vorinostat resistant subclone) M-008277-01 Z-score >=5.13 0.78 none GR00402-S-1 Host restriction factor for the Mycobacterium tuberculosis infection to A549 cells (1) 9411 9411 The percentage of infected cells A549 SIR0003188 Z-score > 5 -2.40402152261272 no effect 5 days post-infection GR00402-S-2 Host restriction factor for the Mycobacterium tuberculosis infection to A549 cells (2) 9411 9411 The percentage of infected cells A549 SIR0003188 Z-score > -3 1.3190980027294879 no effect 5 days post-infection