GenomeRNAi - a database for RNAi phenotypes and reagents

What is GenomeRNAi?

GenomeRNAi is a database containing phenotypes from RNA interference (RNAi) screens in Drosophila and Homo sapiens. In addition, the database provides an updated resource of RNAi reagents and their predicted quality.

RNAi screening data is extracted from the literature by manual curation.

Please remember to cite GenomeRNAi to help us secure future funding. We also appreciate your feedback and suggestions!


the GenomeRNAi database either by viewing all screens, by looking at frequent hitters or by choosing an example below

Genes: 841 , CTNNB1 , Pvr , CG9171 , FBgn0036141
Reagents: DRSC03504 , BKN25930
Phenotypes: regulation , decreased , Toll


  • GenomeRNAi v17 released27 November, 2017
    GenomeRNAi version 17.0 contains a total of 687 RNAi screen: 478 in human and in 209 Drosophila. In order to facilitate the submission and release process, from now it is possible to visualize submitted screens and publications also before the new database version is released. For performance and availability, We switched from DAS to the currently popular bioinformatics file formats bigbed and 2bit in the Genome browser.
    Many thanks to Falkenberg et al. that submitted a screen on an anti-cancer agent sensitivity and to all the users of GenomeRNAi that sent us feedbacks and reactions.

Please cite: Schmidt et al. (2012). GenomeRNAi: a database for cell-based and in vivo RNAi phenotypes, 2013 update.